If you’re an aviation nerd or an erstwhile pilot like me, this sort of thing will be right up your alley.  Malpensa’s an excellent choice if you’re going to start your Italy experience in the north–the fares are usually quite reasonable as it’s a major hub and the train rides you’ll find to Venice, the Lake Region, the rest of the Veneto is pretty regular and quick, and the views along the way are excellent.  The only drawback–public transit options to and from the airport can add considerable travel time as many others have noted.  Getting through Milanese traffic can be a pain, but on net it’s where we’ll often choose to land in Italia.